Addiction to Amphetamine

Addiction to Cocaine and Amphetamine

but not DA reuptake, produce neither significant reinforcement in animal models nor euphoria in humans. Laboratory of Molecular and Developmental Neuroscience Moreover, antidepressants do not produce dependence in humans even with very long-term use. In addition, Massachusetts General Hospital Harvard Medical School lesioning of DA terminals within the NAc or full pharmacological blockade of DA...

An extrapyramidal choreiform syndrome caused by amphetamine addiction.

Four cases are described to demonstrate the extrapyramidal clinical syndrome sometimes appearing in chronic amphetamine users. The symptoms are dominated by choreiform or athetoid movements, ataxia and disturbances of gait. The syndrome develops during amphetamine abuse and may be observed also during abstinence. The symptoms usually disappear within a week when the drug is discontinued, but ma...

Medications Development Research for Treatment of Amphetamine and Methamphetamine Addiction Report to Congress

Misdiagnosed Pruritus; Formication due to Chronic Amphetamine Abuse

Amphetamine abusers are shown to have significant cognitive impairments as well as delusional disorders. We present a 17-year-old man who was admitted to the toxicology emergency department with amphetamine overdose. Along with the classic signs and symptoms of overdose including mydriasis, tachycardia, hypertension, sweating and severe agitation, his urine toxicology screen test was found to b...

Chronic treatment with Delta(9)-tetrahydrocannabinol enhances the locomotor response to amphetamine and heroin. Implications for vulnerability to drug addiction.

Cannabis sativa preparations are some of the most widely used illicit recreational drugs. In addition to their direct addictive potential, cannabinoids may influence the sensitivity to other drugs. The aim of the present study was to determine if a cross-sensitization between Delta(9)-tetrahydrocannabinol (Delta(9)-THC) and other drugs (amphetamine and heroin) could be demonstrated. We examined...